Given the need to comply with product safety requirements and statutory regulations, the pharmaceuticals sector is an industry that demands high production as well as R&D plant and equipment standards. And that certainly includes feeding technology. In addition to absolute precision and ease of cleaning, flexibility is called for especially when formulations have to be adapted and ingredients have to be modified. The bulk ingredients used can vary between powders, powder mixes, pellets and liquids – each exhibiting different flow characteristics from free-flowing to bridging. Kubota Brabender Technologie meets these challenges by providing specially tailored feeders.
Our Hygienic Design equipment also complies with GMP Standards (EU) and FDA Guidelines (USA) that apply to the pharmaceuticals industry.
- Single screw feeder (DSR)
- Twin screw feeder (DDSR)
- Small-size twin screw feeder MiniTwin
Further Information Worth Knowing About Our Bulk Ingredient Solutions for the Pharmaceutical Industry (PDF)
Wet-Granulation
Wet granulation involves the mix of dry primary powders using a granulating fluid. The fluid contains a solvent which can be removed by drying. Kubota Brabender Technologie offers precision feeding for these applications.
Possible feeder
- DDSR, DSR, MiniTwin
Mixer
Kubota Brabender Technologie feeders allow powders used in tablet production to be accurately fed before they are mixed and pressed into tablets. Often multiple feeders are used to precisely follow tablet formulations.
Possible feeder
- DDSR, DSR, MiniTwin
Tablet Press
A tablet is more than compressed powder. It is made up of many ingredients, both active and non-active, often in different layers. These layers are often coated. For example, these coatings make a tablet easier to swallow or allow for a timed release of the active ingredient. Whatever the technology, it is absolutely essential to follow the formulation precisely, ensure a complete audit trail, adhere to the appropriate regulations and meet general manufacturing practices.
Possible feeder
- DDSR, DSR, MiniTwin
Other
Toothpaste for example, contains many different ingredients, such as abrasives, foaming agents, flavoring, aromas, colorants, other additives and active ingredients for prevention of tooth decay. These ingredients are processed in mixers, which must be fed in precise amounts by loss-in-weight feeders.
Possible feeder
- DDSR, DSR, MiniTwin
Interesting Articles on Feeding in the Pharmaceutical Industry
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